HomeBlogDiscover sage and its potent constituent, rosmarinic acid

Discover sage and its potent constituent, rosmarinic acid

Have you heard of sage and its potent constituent, rosmarinic acid ? Orius has crafted a cultivation method that doubles the concentration of this compound.

Garden sage is a well-known aromatic and medicinal plant

Garden sage (Salvia officinalis), belonging to the Lamiaceae family, is a well-known aromatic and medicinal plant. It is a perennial, evergreen shrub with woody stems, grayish leaves, and blue to violet flowers.

Native to the Mediterranean, sage is naturalized in many parts of the world. Traditionally, it was used to promote fertility, as a diuretic, a local anesthetic for the skin, and a hemostatic agent, among other uses.

One of its notable components is rosmarinic acid.

Sage and its rosmarinic acid continue to reveal its secrets

In cosmetology, rosmarinic acid is valued for its antioxidant and anti-inflammatory effects, protecting the skin against damage caused by free radicals and reducing redness and irritation. Its antimicrobial properties make it effective in treating acne and other skin conditions.

In pharmacology, it is studied for its numerous biological activities, including its anti-inflammatory, antimicrobial, antiviral, and anticancer effects. It is used in various treatments to reduce inflammation, combat infections, and even in preliminary research for the treatment of certain types of cancer. Its neuroprotective properties are also of interest for the treatment of neurodegenerative diseases such as Alzheimer's disease (1).

At Orius, our mission is to delve into metabolic pathways, unleashing plants' full potential and boosting the concentration of target molecules.

Orius doubled the concentration of rosmarinic acid within sage

After several phases of testing and improvement, Orius has achieved a concentration of 4.2%, doubling on the highest reported levels in the aerial part of the plant (to the extent of our knowledge within the scientific literature). Our quest doesn’t end there. We have several leads to further increase the level of rosmarinic acid in sage. 

Curious to know how we achieve this? Our proprietary methods are based on extensive biological research coupled with cutting-edge technology. We implement efficient and objective R&D processes to achieve our client’s goals.

The cultivation recipes we develop are exclusive to our clients.

References : 

(1) Guan H, Luo W, Bao B, Cao Y, Cheng F, Yu S, et al. A Comprehensive Review of Rosmarinic Acid: From Phytochemistry to Pharmacology and Its New Insight. Mol Basel Switz. 20 mai 2022;27(10):3292.